New daily persistent headache is a continuous, unremitting headache, notorious for its unresponsiveness to aggressive medical interventions.The underlying pathophysiology of Outdoor Rocking Arm Chair (Set of 2) new daily persistent headache is poorly understood resulting in unending, chronic pain.However, a prior study identified elevated tumor necrosis factor alpha within the cerebral spinal fluid of new daily persistent headache patients.Herein, we report on a patient who suffered with headache for 6 years failing to respond to over 20 different medical treatments, but found drastic improvement and eventual resolution with Venlafaxine.
This drug binds to the 5-HT 2A receptor inhibiting tumor necrosis factor Throws alpha signaling.Therefore, we hypothesize a chronic inflammatory mechanism driving new daily persistent headache pathology.